Comparison between COVID-19 and DHF co-disease with COVID-19 alone in two pediatric sibling patients

  • Suryadi Nicolaas Napoleon Tatura Department of Pediatrics, Prof. DR. R. D Kandou General Hospital/Robert Wolter Monginsidi Army Hospital/Faculty of Medicine, Universitas Sam Ratulangi, Manado, North Sulawesi
Keywords: Corona virus, Dengue, Antibody, DENV, SARS-CoV-2


We report herein the difference between Corona virus disease-19 (COVID-19) and dengue hemorrhagic fever (DHF) co-infection compared with COVID-19 alone in two pediatric sibling patients. This case report highlights a 10-year-old boy with both COVID-19 and DHF who had less severe coagulation disorder than his sister with COVID-19 alone. In a patient with a dual infection, the presence of dengue antibodies may induce immunological protection against COVID-19. We found reports of milder symptoms in patients who had dengue prior to SARS- CoV-2 infection; however, the opposite occured when SARS-CoV-2 infection precedes dengue.


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How to Cite
Tatura S. Comparison between COVID-19 and DHF co-disease with COVID-19 alone in two pediatric sibling patients. PI [Internet]. 28May2024 [cited 13Jul.2024];64(3):281-. Available from:
Case Report
Received 2023-01-11
Accepted 2024-05-28
Published 2024-05-28