Gastrointestinal Aspects of Malnutrition in Children

  • Michael Gracey Gastroenterology and Nutrition Research Unit, Princess Margaret Children's Medical Research Foundation and Department of Child Health University of Western Australia Perth, Western Australia
Keywords: malnutrition; hygiene; nutrition; diarrheal diseases

Abstract

Throughout history mankind has suffered many scourges. In many parts of the world improvements in living standards, hygiene, nutrition, medical care and preventive public health programmes have made many of these infectious , diseases things of the past. However, in the so called "developing" countries, diarrhoeal diseases of infancy and childhood are still major problems which cause many millions of deaths each year (Mata, 1985).

References

1. AGGER, W.A.; MCCORMICK, J.D.; OURWITH, M.J.: Clinical and, microbiological features of Aeromonas Hydrophila- associated diarrhea. J. Clin. Microbiol. 21: 909-913 (1985).
2. BARKER, W.H.: Vibro parahaemolyticus outbreaks in the United States. Lancet i: 552-554 (1974).
3. BERRY, R.J.; BETTELHEIM, K.A.; GRACEY, M.: Studies on enterotoxigenic Escherichia coli isolated from persons without diarrhoea in Western Australia. J. Hyg. (Camb.) 90: 99-106 (1983).
4. BISHOP, R.F.; DAVIDSON, G.P.; HOLMES, I.H.; RUCK, B.J.: Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis. Lancet ii: 1281-1283 (1973).
5. BISHOP, R.F.; DAVIDSON, G.P.; HOLMES, I. H.; RUCK, B.J .: Detection of a new virus by electron microscopy of faecal extracts from children with acute gastroenteritis. Lancet ii: 149-151 (1974).
6. BLACKLOW, N.R.; CUKOR, G.: Viral gastroenteritis. New Engl. J . Med. 304: 397-406 (1981).
7. BLACKLOW, N.R.; DOLIN, R.; FEDSON, D.S.; DU PONT, H.L.; NORTHRUP, R.S.; HORNICK, R.B.; CHANOCK, R.M.: Acute infectious non-bacterial gastroenteritis: etiology and pathogeneses. Ann. Intern. Med. 76: 993-1008 (1972).
8. BLAKE, P.A.; WEAVER, R.E.; HOLLIS, D.G.: Diseases of humans (other than cholera) caused by Vibrios. Ann. Rev. Microbiol. 34: 341-367 (1980).
9. BLASER, M.J.; GLASS, R.I.; HUQ, M.I.; STOLL, B.; KIBRIYA, G.M.; ALIM ARMA: Isolation of Campylobacter fetus subsp. Jejuni from Bangladeshi children. J. Clin. Micro bioi. 12: 744-747 (1980a).
10. BLASER, M.J.; LA FORCE, F.M.; WILSON, N.A.; WANG, W.L.L.: Reservoirs for human campy1obacteriosis. J. Infect. Dis. 141: 665-669 (1980b).
11. BLASER, M.J.; WELLS, J.G.; FELDMAN, R.A.; POLLARD, P.A.; ALLEN, J.R.: Campylobacter enteritis in the United States. Ann. Intern. Med. 98: 360-365 (1983).
12. BOWIE, M.D.; BRINKMAN, G.L.; HANSEN, J.D.L.: Acquired disaccharide intolerance in malnutrition. J. Pediatr. 66: 1083-1091 (1965).
13. BRANDT, C.D.; KIM, H.W.; RODRIQUEZ, W.J.: ARROBIO, J.O.; JEFFRIES, B.C.; STALLINGS, E.P.; LEWIS, C.; MILES, A.J.; CHANOCK, R.M.; KAPIKIAN, A.Z.; PARROTS, R.H.: Pediatric viral gastroenteritis during eight years of study. J. Clin. Microbiol. 18: 71-78 (1983).
14. BRUNSER, 0.; CASTILLO, C.; ARAYA, M.: Fine structure of the small intestinal mucosa ininfantile marasmic malnutrition. Gastroenterology 70: 495-507 (1976).
15. BRUNSER, 0.; FIGUEROA, G.; ARAYA, M.; ESPINOZA, J.: Infectious and diarrheal disease. In: P.L. White and N. Selvey, eds. Malnutrition: Determinatns and Consequences. Alan R. Liss, New York, (1984).
16. BURKE, V.; GRACEY, M.: Aeromonas species in human diarrhoeal disease, J. Gastroenterol. Hepatol. 1: 237-249 (1986).
17. BURKE, V.; GRACEY, M.; ROBINSON, J.; PECK, D.; BEAMAN, J.; BUNDELL, C.: The microbiology of childhood gastroenteritis: Aeromonas species and other infective agents. J. Infect. Dis. 148: 68-74 (1983).
18. BURKE, V.; ROBINSON, J.; GRACEY, M.: Biotyping as a method of screening for enterotoxigenic Escherichia coli. Pathology 19: 80-83, (1987).
19. BURKE, V.; ROBINSON, J.; GRACEY, M.; PETERSON, D.; PARTRIDGE, K.: Isolation of Aeromonas hydrophila from a metropolitan water supply and correlation with clinical iso- · lates. Appl. Environ. Microbiol. 48: 361-366 (1984).
20. CARPENTER, C.C.J.: Clinical and pathophysiological features of diarrhea caused by Vibrio cholerae and Escherivhia coli. In: M. Field, J .S. Fordtran and S.G. Schultz eds. Secretory Diarrhea. American Physiological Society, Bethseda, Maryland, (1980).
21. COOK, G.C.: Aetiology and pathogenesis of postinfective tropical malabsorption (tropical sprue). Lancet i: 721-723 (1984).
22. CHUNG, M.H.; McGILL, D.B.: Lactase deficiency in Orientals. Gastroenterology 54: 225-226 (1968).
23. CRAMBLETT, H.E.; AZINI, P:: HAYNESS, R.E.: The 'etiology of infectious diarrhea in infancy with special reference to enteropathogenic E. coli. Ann. N.Y. Acad. Sci. 176: 80-92 (1971).
24. DAVIDSON, G.P.: Viral Diarrhoea. Clin. Gastroenterol. 15: 39-53 (1986).
25. DAVIDSON, G.P.; BISHOP, R.F.; TOWNLEY, R.R.W.; HOLMES, I.H.; RUCK, B.J.: Importance of a new virus in acute sporadic enteritis in children. Lancet i: 242-246 (1975).
26. DAVIDSON, G.P.; GOODWIN, D.; ROBB, T .A.: Incidence and duration of lactose malabsorptionin children hospitalized with acute enteritis: study in a well-nourished urban population. J. Pediatr. 105: 587-590 (1984).
27. EDITORIAL: Mechanisms in enteropathogenic Escherichia coli diarrhoea. Lancet ii: 1254-1256 (1983).
28. EVANS, D.G.; EVANS, D.J.:. New surfaceassociated heat-labile colonisation factor antigen (CF A/II) produced by enterotoxigenicEscherichia coli of serogroups 06 and 08. Infect. Immun. 21: 638-647 (1978).
29. FREIJ, B.J.: Aeromonas: biology of the organism and diseases in children. Pediatr. Infect. Dis. 3: 164-175 (1984).
30. GRACEY, M.: The contaminated small bowel syndrome: pathogenesis, diagnosis, and treatment. Am. J. Clin. Nutr. 32: 234-243 (1979).
31. GRACEY, M.: Pathogenesis of diarrhoea. pp. 15-29 in Diarrhoeal Disease and Malnutrition ed. by M. Gracey. Churchill Livingstone, Edinburg, (1985).
32. GRACEY, M.: Environmental hygiene, undernutrition and diarrhoea. pp. 336-352 in Paediatric Gastoenterology, Second edition, ed. by C.M. Anderson, V. Burke and M. Gracey. Blackwell Scientific Publications, Oxford (1987).
33. GRACEY, M.; BURKE, V.: Sugar-induced diarrhoea in children. Arch. Dis. Child. 48: 331-336 (1973).
34. GRACEY, M; BURKE, V.; ROBINSON, J.: Aeromonas-associated gastroenteritis, Lancet ii: 1304-13-6 (1982).
35. GRACEY, M.; BURKE, V.; ROBINSON J.: Patterns of intestinal infection in Australian Aboriginal children. Ann. Trop. Paediatr. 3: 35-39 (1983).
36. GRACEY, M.; BURKE, V.; ROBINSON, J.; MASTERS, P.L.; STEWART, J.; PEARMEN, J .: Aeromonas spp. in traveller's diarrhoea. Br. Med. J. 289: 658 (1984).
37. GRACEY, M.; CULLITY, G.J.; SUHARJONO; SUNOTO: The stomach in malnutrition. Arch. Dis. Child. 52: 325-327 (1977).
38. GRACEY, M.; OSTERGAARD, P.; ADNAN, S.W.; IVESON, J.B.: Faecal pollution of surface waters in Jakarta. Trans. R. Soc. Trop. Med. Hyg. 73: 306-308 (1979a).
39. GRACEY, M.; OSTERGAARD, P.; BEAMAN, J.: Oropharyngeal microflora in Aboriginal and non-Aboriginal Australian children. An indicator of enviromental contamination. Med. J. Aust. 2: 212-214 (1979b).
40. GRACEY, M.; STONE, D.E.: Small intestinal microflora in Australian Aboriginal children with chronic diarrhoea. Aust. N .z. J. Med. 3: 215-219 (1972) .
41. GRACEY, M.; STONE, D.E.; SUHARJONO; SUNOTO: Oropharyngeal microflora in malnourished children. Aust. Paediatr. J . 9: 260-262 (1973).
42. GRACEY, M.; SUHARJONO; SUNOTO; STONE, D.E.: Microbial contamination of the gut: another feature of malnutrition. Am. J. Clin. Nutr. 26: 1170-1174 ) 1973).
43. GRIMWOOD, K.; ABBOT, G.D.; FERGUSSON, D.M.; JENNINGS, L.C.; ALLAN, J.M.: Spread of rotavirus within families: a community based study. Br. Med. J. 287: 575-577 (1983).
44. HEYWORTH, B.; BROWN, J.: Jejunal microflora in malnourished Gambian children. Arch. Dis. Child. 50: 27-33 )1975).
45. HIEBER, J.P.; SHELTON, S.; NELSON, J.D.;LEON, J .; MOTTS, E.: Comparison of human rotavirus disease in tropical and te.mperate settings. Am. J. Dis. Child. 132: 853-858 (1978).
46. ITOH, T .; SAOITO, K.; YANAGAWA, Y.; SAKAI, S.; OHASH, M. : Campylobacter in central Sweden. p 5 in Campylobacter ed. by DG Newell, MTP Press, Lancaster (1982).
47. KAPIKIAN, A.Z.; GREENBERG, H.B .; WYATT, R.G.; KALICA, A.R.; CHANOCK, R.M.: The Norwalk group of viruses – agents associated with epidemic viral gastroenteritis. Pp 147-177 in Virus Infections of the Gastrointestinal Tract. Marcel Dekker Ins ., Basel, New York (1982).
48. KARMALI, K.A.; FLEMING, P.C.: Campylobacter enteritis in children. J. Pediatr. 94: 527-532 (1979).
49. KING, C.E.; TOSKES, P.P.: Small intestine bacterial overgrowth. Gastroenterology 76: 1035-1055 (1979).
50. KOHL, S.; JACOBSON, J.A.; NAHMIA, S.A.: Yersinia enterocolitica infections in children. J . Pediatr. 89: 77-79 (1976).
51. LEVINE, M.M; BERQUIST, E.J .; NALIN, D.R.; YOUNG, C.R.; SOTMAN, S.: Escherichia coli strains that cause diarrhoea but do not produce heat-labile and heat-stable enterotoxins and are non-invasive. Lancet i: 1119-1122 (1978).
52. MATA, L.: Global imp.ortance of diarrhoeal disease and malnutrition. pp 1-14 in Diarrhoeal Disease and Malnutrition ed. by M. Gracey, Churchill Livingstone, Edinburgh, (1985).
53. MATA, L.J.; JIMINEZ, F.; CORDON, M.; ROSALES, R.; PRERA, E.; SCHNEIDER, R.E.; YITERI, F.E.: Gastrointestinal flora of children with protein-calorie malnutrition. Am. J. Clin. Nutr. 25: 1118-1126 (1972) .
54. MATHEWSON, J.J.; JOHNSON, P.C.; DuPONT, H.L.; MORGAN, D.R .; THORNTON,S.A.; WOOD, L.V.; ERICSSON, C.D.: A newly recognized cause of travelers diarrhea: enteroadherent Escherichia coli. J. Infect. Dis. 151: 471-475 (1985).
55 . McNEILLY, J .; CICCHINI, C.; OLIVER, D.; GRACEY, M.: Infectious disease in Aboriginal infants and children in Western Australia . Med.J. Aust. 2: 547-551 (1983).
56. MEHTA, A.P.; BOIPHODE, S.H.; AMANT A, P.D.; JAIN, M.K.: Jejunal microflora in malnourished children. In: J .A. Walker-Smith and A.S. McNeish, eds. Diarrhoea and Malnutrition in Childhood, Butterworths, London (1985).
57. MENTZING, L.C.: A water-borne outbreak of Campylobacter in central Sweden. pp 278 in Campylobacter ed. by DG Newell, MTP Press, Lancaster (1982) .
58. MERSON, M.H.; ROWE, B.; BLACK, R.E.: Use of antisera for identification of enterotoxigenic Escherichia coli. Lancet ii: 222-224 (1980).
59. MILLER, D.; CRANE, R.K.: The digestive function of the epithelium of the small intestine. II. Localisation of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells. Biochim. Biophys. Acta 52: 293-298 (1961).
60. MILLERSHIP, S.E.; CHATTOPADHYAY, B.: Aeromonas hydrophila il) chlorinated water supplies. J. Hosp. Infect. 6: 75-80 (1985).
61. MILLERSHIP, S.E.; CURNOW, S.R.; CHATTOPADHYAY, B.: Faecal carriage rate of Aeromonas hydrophila. 1. Clin. Pathol. 36: 920-923 (1983) .
62. MOSELEY, S.L.; ECHEVERRIA, P.; SERIW AT ANA, J.: Identification of enterotoxigenic Escherichia coli by coloni hybridization using three enterotoxin gene probes. J . Infect. Dis. 145: 863-869 (1982).
63. PAl, C.H.; GILLIS, F.; MARKS, M.I.: Infection due to Yersinia enterocolitica in children with abdominal pain. J . Infect. Dis. 146: 705 (1982).
64. RETTIG, P.J.; ALTSHULER, G.P .: Fatal gastroenteritis associated with coronavirus like particles. Am. J. Dis. Child. 139: 245-248 (1985).
65. ROBINSON, D.S.; EDGAR, W.M.; GIBSON, G.L.; MATCHETT, A.A.; ROBERTSON, C.: Campylobacter enteritis associated with the consumption of unpasteurized milk. Br. Med. J. 1: 1171-1173 (1979).
66. RODRIQUEZ, W.J.; KIM, H.W.; ARROBIO, J.D.; BRANDT, C.D.; CHANOCK, R.M.; KAPIKIAN, A.Z.; WYATT, R.O.; PARROTT, R.H.: Clinical features of gastroenteritis associated ith human reovirus-like agent in infants and young children. J. Pediatr. 91: 188-193 (1977).
67 . ROWLAND, M.G.M.: Epidemiology of childhood ddiarrhea in the Gambia. In L.C. Chen and N.S. Scrimshaw, eds. Diarrhea and Malnutrition Interactions, mechanisms and interventions. Plenum Press, New York (1982).
68. ROWLAND, M.G.M.: Bacterial diarrhoeas: contaminated food and water. In: Diarrhoeal Diseases and Malnutrition: A Clinical Update M. Gracey, ed. Churchill Livingstone, Edinburgh (1985).
69. ROWLAND, M.G.M; BARRELL, R.A.E.; WHITEHEAD, R.G.: Bacterial contamination in traditional Gambian weaning foods. Lancet i: 136-138 (1978).
70. ROWLAND, M.G.M.; McCOLLUM, J.P.K.: Malnutrition and gastroenteritis in the Gambia. Trans. Roy. Soc. Med. Hyg. 71 : 199-203 (1977).
71. SANTOSO, H.; AGUNG, I.G.N.; ROBINSON, J.; GRACEY, M.: Faecal Aeromonas spp. In Balinese children. J. Gastroenterol. Hepatol. I: 115-118 (1986).
72. SANYAL, S.G.; SINGH, S.J.; SEN, P.C.: Enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides. J. Med. Microbioi. 8: 195-198 (1975).
73. SAVAGE, A.; DUNLOP, D.: Terminal ileitis due to Yersinia pseudotuberculosis. Br. Med. J. 2: 916-917 (1976).
74. SCHNEIDER, R.E.; VITERI, F.E. : Morphological aspects of the duodenojejunal mucosa in protein-calorie malnourished children and during recovery. Am. J. Clin. Nutr. 25: 1092-1102 (1972).
75." SEBODO, T.; SOETARJO; SADJIMIN, T.; SOENARTO, Y.; SANBORN, W.T.: Study on the etiology of diarrhea. Trop. Pediat. Envir. Chid. Hlth. 24: 107-109 (1978).
76. SEIDLER, R.J.; ALLAN, D.A.; LOCKMAN, H.; COLWELL, R.R.; JOSEPH, S.W.; DA1- L Y, O.P.: Isolation, enumeration and characterization of Aeromonas from polluted waters encountered in diving opertaions. Appl. Environ. Microbial, 29: 1010-1018 (1980).
77. SILVA, R.M.; TOLEDO, M.R.F.; TRABULSI, L.R.: Biochemical and cultural characterisitics of invasive Escherichia coli. J. Clin. Micro bioi. II : 441-444 (1980).
78. SIMON, G.L.; GORBACH, S.L.: The human intestinal microflora. Dig. Dis. Sci. 31: 147S- 162S (1986).
79. SKIRROW, M.B.: Campylobacter enteritis: a "new" disease. Br. Med. J . ii: 9-11 (1977).
80. SPRINZ, H.; SCRIBHIBHADH, R; GANGAROSA, B.J.; BENYAJATI, C.; KUNDEL, D.; HALSTEAS, S.: Biopsy of small bowel in Thai people. With special reference to recovery from Asiatic cholera and to an intestinal malabsorption syndrome. Am. J. Clin. Path. 38: 43-51 (1962).
81. THELEN, P.; BURKE, V.; GRACEY, M. : Effects of intestinal microorganisms on fluid and electrolyte transport in the rat. J. Med. Microbioi, 11: 463-470 (1978).
82. TOMKINS, A.: Tropical malabsorption: recent concepts in pathogenesis and nutritional significance. Clin. Sci. 60: 131-137 (1981).
83. TOMKINS, A.M.; DRASAR, B.S.; BRADLEY, A.K.; WILLIAMSON, W.A. : Water supply and nutritional status in rural northern Nigeria. Trans. R. Soc. Trop. Med. Hyg. 72: 239-243 (1978).
84. TSUKAMOTO, T .; KINOSHITA, Y.; SHIMADA, T.; SAKAZAKI, R. : Two epidemics of diarrhoeal disease possibly caused by Plesiomonas shigelloides. J . Hy. 80: 275-280 (1978).
85. UHNOO, 1.; WADELL, G.; SVENSSON, L.; JOHANSSON, M.E.: Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children. J. Clin. Microbioi. 20: 365-372 (1984).
86. VITERI, F.E.; SCHNEIDER, R.E. : Gastrointestinal alterations in protein-calorie malnutrition. Med. Clin. N. Am. 58: 1487-1505 (1974).
87. WATERLOE, J.C. : Amount and rate of disappearance of liver fat in malnourished infants in Jamaica. Am. J. Clin. Nutr. 28: 1330-1336 (1975).
88. WENMAN, W.M.; HINDE, D.; FELTHAM, S.; GURWITH, M.: Rotavirus infection in adults: results of a prospective family study. New Engl. J. Med. 301: 303-306 (1979).
89. WHARTON, B.A.: Gastroenterological problems in children of developing countries: In: Anderson, C.M., Burke, V., eds Paediatric Gastroenterology pp. 569-610. (Blackwell Scientific Publications, Oxford 1975).
90. WHARTON, B.A.; HOWELLS, G.; PHILIPS, 1.: Diarrhoea in Kwashiorkor. Br. Med. 1. 4: 608-611 (1968).
Published
2019-07-25
How to Cite
1.
Gracey M. Gastrointestinal Aspects of Malnutrition in Children. PI [Internet]. 25Jul.2019 [cited 25Apr.2024];28(3-4):85-6. Available from: https://www.paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2248
Section
Special Article
Received 2019-07-25
Published 2019-07-25